Azeotrope Refrigerants vs. Zeotrope

HVAC refrigerant bottles

Azeotrope Refrigerants vs. Zeotrope

After reading this article, check out a short podcast on this subject.  

Do you understand your refrigerant?

Do you listen to it or communicate with it… wipe its tears when it’s sad?

Yeah, probably not, but it is essential to understand some terminology to understand your refrigerant’s deepest, most inner feelings. 

Not all refrigerants are pure compounds, such as R22 and R134a, and not all refrigerants are created equal.  

Azeotropic Blends

An azeotropic refrigerant is a mixture of two or more components that boil at the same temperature. 

The components in this type of refrigerant will evaporate and condense together as one.

An example of an azeotropic refrigerant is R502

There is no glide to worry about with this type of mixture.

Zeotropic Blend

A zeotropic blend is also a mixture of two or more components.

The components of this refrigerant have different boiling points. 

These components will evaporate and condense at different temperatures. 

An example of a zeotropic blend is any 400 series refrigerant, such as R407c and R410a, keeping in mind that R410a is considered a near azeotropic blend.   

To fully understand zeotropic blends, we must also understand fractionation and glide.


Imagine a jug of R407c, which is a mixture of three components, sitting in a room under normal conditions. 

The components will boil off at different temperatures separating from the liquid mixture. 

Think of the three vapor components separated in the jug occupying their own space above the liquid.

This is known as fractionation. 

Because these components have different properties, more of one gas may be at the top of the jug than the other. 

As fractionation occurs, the vapor blend that hovers above the liquid is compromised; it’s not a complete mixture. 

This is why it’s important to charge this type of refrigerant as a liquid to ensure the system receives the full blend. 

One thing to keep in mind when charging, the refrigerant must leave the jug as a liquid, but it can be flashed into the system as a vapor. 

Actually, it is recommended that it is flashed into the system to avoid liquid entering the compressor.  

Check Out Yellow Jacket’s Liquid Charge Adapter

Azeotrope Refrigerants vs Zeotrope: yellow jacket liquid charge adapter


Glide is a term that confuses some techs I’ve found, but if explained properly it doesn’t need to be a brain-numbing exercise. 

Glide is the difference between the boiling point of the most volatile component compared to the least volatile component within the refrigerant blend. 

So, for example, if one component were to boil at 100 degrees Fahrenheit and the other at 110 degrees Fahrenheit, that would be 10 degrees of glide. 

When looking at a PT chart, you will see bubble point (point of evaporation) and dew point (point of condensation).

The space between these two points is considered the refrigerant’s glide.  

Now go love your refrigerant!

Share this article on:

Gary McCreadie

Gary McCreadie is an HVAC tech, the creator of, the HVAC Know It All Podcast, and owner of McCreadie HVAC & Refrigeration Services

Follow us on:

Save 8% on purchases at TruTech Tools with code knowitall (excluding Fluke and Flir products)

Save 8% at eMotors Direct with code HVACKNOWITALL

About Our Blog

HVAC Know It All was created by Gary McCreadie, a licensed refrigeration and gas technician, with three goals in mind:
Learn. Teach. Entertain.
All within a positive environment.

Happy HVACing…



Subscribe Now!

Subscribe now and stay up to date with the latest industry trends and HVAC tips and tricks!

Subscribe Now!

Subscribe now and stay up to date with the latest industry trends and HVAC tips and tricks!