Key Takeaways
- R-454B (Puron Advance): Leading R410a replacement with GWP of 466, similar operating pressures, but classified as A2L (mildly flammable)
- R32 Performance: Single-component refrigerant offering higher capacity than R410a with GWP of 675, already used by Daikin and LG
- Safety Classifications Matter: New refrigerants shift from A1 (non-flammable) to A2L (mildly flammable), requiring updated handling procedures
- Chiller Solutions Available: R513A replaces R134a in screw chillers while R514A replaces R123 in centrifugal units, both maintaining A1/B1 classifications


